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Showing posts with label South China Morning Post. Show all posts
Showing posts with label South China Morning Post. Show all posts

Thursday 22 September 2016

New ways to beat superbugs, a Malaysian doctorate student discovered?


A Malaysian doctorate student is causing a buzz in the medical research field.

 Lam Shu Jie (pic), 25, and her team of researchers may have found a solution to the antibiotic-resistant bacteria commonly known as “superbugs”.

The team from Melbourne School of Engineering published a paper on Monday on a new treatment method.

Shu Lam A 25 year-old Melbourne Uni student has made a discovery that could be a game-changer for modern medicine and avert a serious health crisis.

The method uses star-shaped structures called structurally nano-engineered anti-microbial peptide polymers (SNAPPs).

SNAPPs are found to be highly effective in killing Gram-negative bacteria – a class of bacteria which is antibiotic resistant – without hurting healthy cells, according to the team’s article in Nature Microbiology.

Unlike antibiotics which attempt to kill the bugs chemically, the star-shaped protein molecules defeat them by “ripping apart their cell walls”.

She also found that it was important to have outside interest due to the research work's long hours and possibility of failure..

"I've just watched the Korean movie called 'Train to Busan'. I also like trying new cuisines and exploring cafes here because the food culture's very strong," she laughed..

She lamented that the initial experiments were daunting, which left her in fear..

"My experiments kept failing, but later I learned what went wrong. I like the investigating part of research. It's beyond being in the labs or reading books; it's also about speaking with other experts," she said..

The second child of three siblings still has strong ties with home..

"I try to come back for the Chinese New Year because I miss my family," she said while lamenting the loss of her father last year..

Despite her supervisor Prof. Greg Qiao reportedly saying that her research is still at its early stage, Lam has plans to continue her research in the field, while in the long-term, she expressed hope to establish a research group with experts upon returning home and also lecture..

She will complete her PhD in two months time..

The scientific breakthrough was picked up by many news portals including Science Daily, the Australian Broadcasting Corporation and the South China Morning Post.

Lam told South China Morning Post that she spent the past three and a half years researching polymers and how they can be used to kill antibiotic-resistant bacteria.

The Batu Pahat lass, who is to submit her PhD thesis in two months, admitted that she hoped to continue to work in research, rather than opt for medical training like her father who is a paediatrician.

“I think my career will be mainly focused on research in the medical field,” said Lam.

Her supervisor Prof Greg Qiao, who is also one of the 10 co-authors of the scientific journal, said the research was still in its early stages.

He told South China Morning Post that more work was needed to verify the best formula and structure, as well as determine dosage and test for toxicity, before the substance could be deemed safe for human use.

“Even with all the money in the world, it would take at least five years to get to the first human-test stage because many resources and much work are needed before commercialisation,” he said.

Superbugs stem from misuse or overuse of antibiotics, according to the World Health Organisation.

It lists anti-microbial resistance as a global concern that threatens our ability to treat common infectious diseases, resulting in prolonged illness, disability and death. The Star/Asia News Network.

Related:

The 25-year-old Malaysian Chinese who may have just solved the ...

www.scmp.com › This Week in Asia › Society
South China Morning Post
6 days ago - South China Morning Post .... The World Health Organisation lists superbugs as a key threat to human ... I have developed an interest in food and really like exploring new cafes ... Lam moved to Australia for her foundation studies after finishing .... Peter Wong says tougher banking regulation is on the way.

“I think my career will be mainly focused on research in the medical field,” said Lam, who has already begun pursuing her passion in polymer research during her four-year undergraduate degree in chemical and biomolecular engineering.

“As an undergraduate, she would come to our group for summer work when she had time,” Qiao recalled of Lam.


These days when Lam finds the rare downtime between researching polymers, she likes to watch TV and explore the city. “Being in Melbourne, I have developed an interest in food and really like exploring new cafes and brunch places, so I spend a lot of time trying new food and walking around when I’m not working,” Lam said.

Lam moved to Australia for her foundation studies after finishing primary and secondary school in Malaysia, and is likely stay on in Australia after graduating at the end of the year.

“My main preference would be to continue to stay in research, but I am also looking at career fields outside of polymer research,” she said. “This research is going in different directions,” said Qiao. “One is killing the bug, the other is treating cancer.”

Her group is also examining the use of polymers as a drug carrier for cancer patients as well as the treatment of other diseases.

A key project at the moment is the synthetic transplant of cornea in the eye, which involves the use of polymers grown from the patient’s own cells in the lab to replace the damaged cornea.
The operation has already been tested multiple times successfully on sheep, and Qiao hopes to begin the first human trials in Melbourne within two years, working with the Melbourne Eye and Ear Hospital.


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Superbug lurking! Drug resistance now a nightmare!

Mar 18, 2013 ... In addition, no new major antibiotics have been made since the late 1980's because antibiotics can have a short lifespan before superbugs ...


May 5, 2014 ... WHO's Alarm Bells: Antibiotic Resistance Now a 'Major Threat to Public ... There hasn't been a new class of antibiotics developed since the late ..


May 6, 2014 ... ... Bacteria , hand hygiene , Health , health and wealth , Hepatitis , Immunity , Medicare , medicines , MRSA , superbugs , Vaccines , WHO ...
 

Monday 9 July 2012

China builds nuclear-powered deep-sea station

Not content with ambitious plans to dominate space exploration over the coming decades, China is also looking to master the ocean with the development of a deep-sea station which could be its first step towards large-scale underwater mining.


Plans for the nuclear powered mobile deep-sea station were unveiled earlier this year by China Ship Scientific Research Centre – the state-owned venture whose Jiaolong manned submersible recently reached depths of over 7,000 metres – according to South China Morning Post.

The craft would have dimensions of 60.2m x 15.8m x 9.7m, weigh about 2,600 tonnes, and have enough room for 33 crew members.

It would have propellers to move submarine-like underwater and several ports to allow smaller craft to dock with it, the report said.

On that note, a smaller prototype which could carry 12 crew on an 18-day expedition is currently in production, with an expected delivery date of 2015.

While China’s plans in space appear to revolve heavily around military strategy, its deep sea efforts have more to do with the country finding an answer to its current energy problems.

Drilling for oil and mining copper and other natural resources both appear to be high on the list of China’s deep-sea priorities, although technological limitations may hold back advances in the project for some time, the report claims.

When China wants something it usually succeeds in the end, however, so it would not be out of the question to see the launch of a full-sized deep-sea station by 2030, according to SCMP.

As with most elements of Chinese technology innovation, the PLA is never too far away – this deep-sea project is apparently funded by 863 Program, a hi-tech state scheme.

By Phil Muncaster
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Related post:

China set to launch bigger space programme

Science

China plans nuclear deep-sea mining base


A Chinese company is set to build a nuclear-powered mobile deep-sea station in the western Pacific, according to local reports.

The China Ship Scientific Research Centre's proposed station -- which will have huge propellers to enable free movement in the ocean depths -- will be manned by 33 crew for up to two months at a time and powered by a nuclear reactor.

Its main goal, according to reports in the South China Sea Post, will be to mine for precious metals. The nation, which recently announced it is stockpiling rare earth elements amid fears of shortages, would use the facilities to hunt mainly for copper, lead, zinc, silver, gold and oil.

Underwater mining is typically a costly affair, full of potential dangers and problems. Canadian-owned Nautilus Minerals Inc was the first commercial copper-gold mining venture to be granted permission to explore the Bismarck Sea floor surrounding Papua New Guinea, but has already run into problems with environmentalists warning the mining could destroy marine life and cause devastating oil spills. China's Tongling Non-ferrous Metals Group had signed up as the project's very first customer in April 2012, but a dispute with Papua New Guinea also stands to halt the mining project's 2013 launch completely

The Chinese company appears to be wary of these issues, and is therefore treading carefully, with plans for the bold venture slated for a more reasonable 2030 launch -- according to experts the South China Sea Post spoke to -- and a smaller 12-crew prototype capable of 18-day dives set to launch by 2015. The larger 60-metre-long craft will weigh in at 2,600 tonnes.

In preparation, the China Ship Scientific Research Centre has been engaging in test dives of manned vehicles -- its Jiaolong model reached a record-breaking 7,020 metres at the Mariana Trenchin the Pacific Ocean on the same day that China's Shenzhou-9 spacecraft docked at the Tiangong 1 space station.

Reports suggest that the project is being funded by the state's 863 Program, a fund specifically for the development of innovative technologies, which has links with the military. Nevertheless, mining for oil and copper seem to be the most likely priorities on the agenda, with crew on the station able to spend two months at a time living and mining underwater.

Shanghai is hosting the 41st Underwater Mining Institute conference October 2012, and further details could potentially be revealed then. In the meantime, a look at the China Ship Scientific Research Centre's website reveals fields of interest that range from manned submersibles such as the Jiaolong vessel to atmospheric one-man diving suits and autonomous underwater robots -- the latter would be exponentially beneficial in aiding aquanauts during danger-filled underwater mining missions.

The centre also appears to be keen on waterslides. Definitely one to watch.

By Liat Clark WIRE. UK. CO